Creative Bioarray announced the release of its cell immortalization service which significantly extend replicative capacity of target cells and boost to establish personalized cell lines for customers.
cell immortalization service which significantly extend replicative capacity of target cells and boost to establish personalized cell lines for customers.— Creative Bioarray, a global innovative biotechnology company focuses on developing unique technologies and high-quality products, today announced a release of its
Creative Bioarray has developed a proprietary cell immortalization service for research applications. Primary cells usually stop proliferation, senescence and death after a limited number of cell passages. This limits the further application of cell culture technology. Immortalized cells are derived from primary cells, and exogenous immortalized genes are introduced into target cells through gene transfection technology, thereby establishing immortalized cell lines to achieve cells cultured in vitro. The purpose is to proliferate indefinitely, with no difference between cells.
Primary cells only undergo a predetermined limited number of cell divisions during the cultivation process, but after a limited population multiplies (the number varies according to species, cell type and culture conditions), the primary cells enter a state called replication aging, They are no longer divided. Therefore, scientists often need to rebuild a new culture-a complex and long process. Compared with primary cells, immortal cells can solve this problem to a certain extent. Introduce exogenous immortal genes into target cells through gene transfection technology to establish immortal cell lines, so that cells cultured in vitro have proliferative ability, and there is no difference between cells. Immortalized cells can be delivered continuously, allowing scientists to use the same consistent cells throughout the research project.
Immortalized cell lines provide scientists with insights into the biological processes of human cells and have become a powerful tool for countless applications, including testing drug metabolism and cytotoxicity, studying gene function, and producing vaccines, antibodies and biological compounds.
Although immortalized cell lines are essential for biomedical research, establishing new cell lines can be tricky and frustrating. With rich experience in cell-based immortalization, scientists in Creative Bioarray have been able to successfully immortalize various mammalian cells using different methods of immortalization, such as immortalized liver cells and immortalized microglia. If you have special needs, Creative Bioarray also provides customized cell immortalization services for your unique solutions.
“With years of in-depth study in cell immortalization, Creative Bioarray has developed the most comprehensive range of cell immortalization products, including recombinant lentiviruses expressing EBV, HPV-16 E6/7 and SV40 T antigens, retroviruses (MMLV) and adenovirus, hTERT, p53 and RB siRNA and ras&myc mutants. All these tools will make your cell immortalization project easier than ever.” explained Hannah Cole, the marketing director of Creative Bioarray.
About Creative Bioarray
Founded in 2005, Creative Bioarray is dedicated to offering customers with innovative biotechnology products and services for research use to greatly enhance and drive innovation and standards in science. As a well-recognized industry leader with more than 10 years of experience and in-house experts supported, Creative Bioarray has already countenanced research all around the world.
Release ID: 88959413