NGS-Based HLA Typing & Matching Article Shows New Method For Library Preparation

Share This Press Release has published its latest article covering some of the important aspects of a new method to determine and match HLA type. The articlewhich is aimed primarily at Bioscientists. The article is available for viewing in full at has published a new article entitled “NGS-Based HLA Typing Delivers More Comprehensive Information”, which sheds light on the most important aspects of some of the important aspects of a new method to determine and match HLA type. Bioscientists, and other interested individuals, can view the full article at

The article includes several interesting pieces of information, one in particular is that a next generation sequencing protocol is available for high-throughput and more accurate HLA typing. This should be of particular interest to bioscientists because an optimized protocol that includes DNA size selection can open the field for analyzing new alleles and genotypes.

One of the most important piece of information the article tries to convey is that DNA size selection is critical for optimization of this protcol. The best example of this is perhaps found in the following extract:

‘Used for matching organ transplants to donors and other applications, human leukocyte antigen (HLA) typing is rapidly shifting from older methods to NGS technologies. This is a major step forward, as more complete views of the highly polymorphic HLA genes provide a deeper understanding of how a person’s natural genetic variation might affect transplant matches and other immune-related functions.’

In discussing the article’s creation, Dr. Amanda Welch, Editor-in-Chief at said, “This article presents information about a new advance in HLA typing. Accurate and precise HLA matching is critical for clinical applications as well as research applications. DNA size selection is one important aspect of this protocol, and we hope that our readers can apply it to their own research..”

This article is part of BitesizeBio’s Sponsored Education series, and is produced with the assistance of Sage Science. Sage Science develops products for the life sciences research markets. Their mission is to provide new systems to streamline and improve sample preparation workflows for DNA and protein analysis. now welcomes comments and questions from readers, in relation to the article, which can be posted on the webpage. is used by individual scientists and companies to share their wisdom, know-how and solutions, to creating what has been called “The Missing Manual for Bioscientists”. The website is used, loved and depended-upon by hundreds of thousands of visitors each month.

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Contact Info:
Name: Dr. Nick Oswald
Email: Send Email
Organization: Science Squared Ltd.
Address: The Vision Building 20 Greenmarket, Dundee DD1 4QB, United Kingdom

Source: PressCable

Release ID: 208390