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Historical tragedy of thalidomide without tests on NHPsIn 1957, the thalidomide with good sedative effect on the central nervous system was launched, when it was the birth peak after World War II. The drug was sold to Africa, Latin America, Australia, Japan, Canada and other countries. However, it was proved to be the culprit of more than 10,000 short-legged babies born in the following years. During the clinical testing stage of that drug, there were no side effects showing from the rats that lack in enzyme to transform thalidomide into harmful isomer, which later led to the overlook of possible aftermath on human beings. It was not until 1972 when Poswilo’s team firstly adopted marmoset, which revealed teratogenicity similar to human, initially awaking global researchers to the importance of using NHPs in clinical tests.
Strong points of NHP
The terrifying case shows that non-human primates play irreplaceable role when testing the safety and effectiveness of drugs. The application of monkeys in medical field is beneficiary mainly due to their similarities to people in genetics, anatomy, physiology features that are the core to building models for drug tests, disease study (especially for Zika and Ebola), some of which aspects are quite discrepant with those in rodents. As a conscientious CRO, Creative Biolabs holds bank of biological products from various monkey types, including but unlimited to, Cynomolgus Monkey, Rhesus Monkey, Africa Green Monkey, Baboon (Papio Anubis), Cebus, Chimpanzee, etc.
Catalog:
Blood Sample: The blood samples are provided in 3 formats. Whole blood containing blood cells (red blood cells, white blood cells, platelets) and plasma. Sex-optional-serum—the upper layer of pale yellow transparent liquid of non-anticoagulated blood, can be provided as pooled or individually. Plasma—upper pale yellow liquid after adding anticoagulant determined by the clients.
Tissues: Nearly all sectors of monkeys’ bodies can be accessed at Creative Biolabs, like heart, parotid, ovary, tonsil, lung, etc., covering monkey cardiovascular system, nervous, muscular, even visual system and so on.
Body Fluid: Both extracellular fluid and tissue fluids, from healthy or disease NHPs are offered as requested by customers to facilitate laboratory experiments, composing monkey urine, bone marrow, cerebrospinal fluid (CSF), saliva, etc.
Primary Cells: There is a full list of primary cells, among which the peripheral blood mononuclear cells (PBMCs) are receiving popularity among customers that are working on novel therapeutic methods or improving diagnostic modes targeting specific diseases. All of the products at Creative Biolabs can fit in with various tests and assays such as cell-cell interaction, adhesion, migration, PCR, Western blot, immunoprecipitation, and more.
In biomedical research, animal experiment is the transition of applying basic research results to clinical research, bridging the gap between in vitro research and clinical practice. Although rodents are the most widely applied experimental animals, non-human primates can never get replaced in that there are differences between human and rodent in physiology and anatomy, which might lead the experimental data unable to be directly applied to human beings. Creative Biolabs’s bank of high-standard NHP tissues and cells obtained from even rarely-used monkeys will help solve the problem in a cost-effective manner. Details are available at https://www.creative-biolabs.com/nhp-biologicals/.
About the Company
Creative Biolabs, with over 10 years’ history, is a world-leading life-science company dedicated to providing high-standard NHP products that are supported by well-experienced scientific staff. Substantial resources of non-human primates can guarantee all orders get delivered on time.
Contact Info:
Name: Candy Swift
Email: Send Email
Organization: Creative Biolabs
Address: 45-1 Ramsey Road, Shirley, NY 11967, USA
Phone: 1-631-619-7922
Website: https://www.creative-biolabs.com/nhp-biologicals/
Release ID: 88937925
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