As an expert in stem cell services, Creative Biolabs has upgraded its cover-all induced pluripotent stem cell services to facilitate global scientists with related research, including iPSC differentiation, iPSC reprogramming, cell-based organoid services and iPSC genome editing services.
— In recent years, investigators turn their focuses on induced pluripotent stem cells (iPSCs). The idea that a patient's tissues could transform into a copious, immune-matched supply of pluripotent cells has captured the imagination of researchers worldwide.
With years of exploration in stem cells, Creative Biolabs’ stem cell program has updated its one-stop iPSC services to enhance clients’ research and data relevancy by acquiring and reprogramming iPSCs from a specific patient clinical profile. The pipeline is designed to meet the clients’ project and specific assay requirements for cellular characteristics and functions.
•iPSC Differentiation Services
With the well established iPSC technology platform, Creative Biolabs has the capability to generate iPSC from patient material, either normal or diseased. A variety of cell types can be generated from these iPSCs, such as neuronal cells, hepatocytes, and cardiomyocytes, ocular cells, blood cells, digestive system cells and osteogenic cells differentiation.
“Until now, a variety of approaches have been developed for producing iPSC-derived neurons and many are available here,” said a senior scientist at Creative Biolabs, “including the novel approach—using forced expression of neurogenin-2 with puromycin selection to produce extremely pure networks of glutamatergic neurons from human embryonic stem cells and iPSCs.”
•iPSC Reprogramming Services
Creative Biolabs is dedicated to providing several viable and cost-effective methods for stem cells reprogramming, employing advanced iPSC reprogramming factor delivery strategy by virus (retro- and lentivirus, lentiviral plus cre-lox mediated transgene excision, adenovirus, etc.), iPSC reprogramming factor delivery by episomal vectors, as well as other iPSC reprogramming methods (mRNA, protein) to help clients obtaining the desired iPSC.
Organoid has been described to encompass all 3D organotypic cultures originated from primary tissues, embryonic stem cells (ESCs)/ iPSCs, established cell lines, and whole or segmented organs.
Creative Biolabs is equipped with skillful staff and years of service experience so that experiments can be easily controlled by pure cultures of specific tissues whilst advances in bioengineering mean exact modeling, reflecting complex procedures. The comprehensive organoid services cover cerebral, thyroid, thymic, hepatic, pancreatic, gut, intestinal, gastric, etc. The lung organoid service and kidney organoid service are two focuses of Creative Biolabs.
•iPSC Genome Editing Services
Nowadays, the application of custom-engineered sequence-specific nucleases enables genetic changes in human cells to be easily made with much greater efficiency and precision. Creative Biolabs is dedicated to providing a full range of iPSC genome editing services, including ZFN, CRISPR/Cas9, and TALEN, to knock out a gene of interest, knock in a disease-associated point mutation, tag a gene of interest or reverse to wildtype in disease-derived iPS line.
With world-class expertise in the derivation, bioprocess scale-up, and differentiation of induced human pluripotent stem cells, the services team of Creative Biolabs can finish the iPSC projects and provide pluripotent stem cells to clients in as little as 16-24 weeks. More information can be found on https://www.creative-biolabs.com/stem-cell-therapy.
About Creative Biolabs
With more than 15 years of experience as well as an unrelenting drive in the biotechnology research area, Creative Biolabs has executed every strategy to serve comprehensive stem cell services and products for clients on a worldwide scale. Scientists in Creative Biolabs will be more focused on developing first class product and technology to meet the need of stem cell therapy development.
Name: Bella Smith
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Organization: Creative Biolabs
Address: 45-1 Ramsey Road, Shirley, NY 11967, USA
Release ID: 88968675